Caffeine Doesn't Make You More Alert

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1. Cognitive Decline Begins In Late 20s, U.Va. Study Suggests
   A new study indicates that some aspects of peoples' cognitive skills - such as the ability to make rapid comparisons, remember unrelated information and detect relationships - peak at about the age of 22, and then begin a slow decline starting around age 27.
2. Predicting Not To Predict Too Much: How The Cellular Machinery Of Memory Anticipates The Uncertain Future
   Although the faculty of memory holds information about the past, it is mostly about the present and the future, because it permits adaptive responses to ongoing events as well as to events yet to come. Since many elements in the future are uncertain, the plasticity machinery that encodes memories in the brain has to operate under the assumption that stored information is likely to require fast
3. See It With Feeling: Affective Predictions During Object Perception
   People see with feeling. We "gaze," "behold," "stare," "gape," and "glare." In this paper, we develop the hypothesis that the brain's ability to see in the present incorporates a representation of the affective impact of those visual sensations in the past. This representation makes up part of the brain's prediction of what the visual sensations stand for in the present, including how to act on
4. Structured Event Complexes In The Medial Prefrontal Cortex Support Counterfactual Representations For Future Planning
   We propose that counterfactual representations for reasoning about the past or predicting the future depend on structured event complexes (SECs) in the human prefrontal cortex ("What would happen if X were performed in the past or enacted in the future?").
5. Cortical And Subcortical Predictive Dynamics And Learning During Perception, Cognition, Emotion, And Action
   An intimate link exists between predictive and learning processes in the brain. Perceptual/cognitive and spatial/motor processes use complementary predictive mechanisms to learn, recognize, attend, and plan about objects in the world, determine their current value, and act upon them. Recent neural models clarify these mechanisms and how they interact in cortical and subcortical brain regions.