Treatment-Resistant Bipolar Disorder

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1. Bipolar Disorder Amongst Children And Adolescents Receive Late Diagnosis
   A new study finds that 75% of the cases of paediatric bipolar disorder are diagnosed late – up to 18 months – due to the symptoms manifesting themselves in a different manner depending on whether the patient is a child or adult.
2. Young Adults May Outgrow Bipolar Disorder
   Bipolar disorder, or manic-depression, causes severe and unusual shifts in mood and energy, affecting a person's ability to perform everyday tasks. With symptoms often starting in early adulthood, bipolar disorder has been thought of traditionally as a lifelong disorder. Now, researchers have found evidence that nearly half of those diagnosed between the ages of 18 and 25 may outgrow the disorder
3. rTMS May Be Effective in Patients With Treatment-Resistant Bipolar Depression
   Repetitive transcranial magnetic stimulation (rTMS) may be an effective therapy for treatment-resistant bipolar depression, according to the results of a recent pilot study led by Guohua Xia, MD, PhD, assistant clinical professor of psychiatry at the University of California, Davis.
4. New Algorithms for the Management of Treatment-Resistant Bipolar Depression
   Current guidelines for the management of bipolar depression are outdated because they are based on the definition and treatment of unipolar depression, according to Eduard Vieta, MD, PhD, director of the bipolar disorders program at the University Clinic Hospital of Barcelona, Spain. Dr Vieta led a study to create new definitions and algorithms for the management of treatment-resistant bipolar I
5. Offspring of Parents With Bipolar Disorder
   It is generally held that the offspring of parents with bipolar disorder (BD) are at risk for BD. The degree of risk is an important question for both clinicians and parents. A recent study of bipolar offspring by Birmaher and colleagues1 sheds light on this issue.